产品货号：
Z23151
中文名称：
PELI1抗体
英文名称：
Anti-PELI1 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-PELI1 Antibody |
| 指标别名 | PELI1;Pellino 1;pellino homolog 1 (Drosophila);PRISM;Protein pellino homolog 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | PELI1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Rabbit polyclonal Pellino 1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human Pellino 1.The immunogen is located within amino acids 300 - 350 of Pellino 1. |
| 计算分子量 | 46kDa |
| 成分 | Pellino 1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Pellino 1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The Pellino proteins are a highly homologous family of E3 ubiquitin ligases that act as upstream mediators in Toll-like receptor (TLR) pathways that lead to activation of MAP kinases and transcription factors.Pellino 1 is required for interleukin-1-mediated signaling through its interaction with the IRAK4-IRAK-TRAF6 complex,ultimately resulting in the activation of NF-百B.Like other members of the Pellino family,Pellino 1 is an E3 ubiquitin ligase,able to catalyze the polyubiquitination of IRAK1.It is activated via phosphorylation by either IRAK1 and IRAK4 or the IKK-related kinases IKK-汍and TBK1.In addition to phosphorylation,Pellino 1 activity is also modulated via ubiquitination and sumoylation. |
| Uniprot ID | Q96FA3 |
| 基因名全称 | Pellino E3 ubiquitin protein ligase 1 |
| 蛋白名全称 | Pellino E3 ubiquitin protein ligase 1 |
| 推荐稀释比 | Pellino 1 antibody can be used for detection of Pellino 1 by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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